Contact us at (800) USC-CARE (800-872-2273)

Clinical Trials and Research Projects

Clinical Trials and Research Projects2019-02-06T12:01:50+00:00

Our research group is committed to the pursuit of basic and clinical knowledge that can advance treatments and care for individuals with multiple sclerosis. Toward these goals, we are conducting clinical trials and basic science studies for MS patients, described below.

The following are clinical trials currently open for enrollment:

  • Study of Tysabri in Early Relapsing Remitting Multiple Sclerosis in Anti-JCV Antibody Negative Patients
  • MS Study Evaluating Safety and Efficacy of Two Doses of Fingolimod Versus Copaxone
  • Exploratory Study to Assess Clinical Response to Gilenya® (Fingolimod) in Relapsing Remitting Hispanic Multiple Sclerosis Forms
  • Assessing Induction of Type II (M2) Monocytes/Macrophages in Patients Receiving Gilenya
  • Ampyra in Female Sexual Function
  • Hispanic Ancestry Multiple Sclerosis Registry at USC

For information about any of these trials, you may contact the individuals who are listed with each trial or study below, or you may contact us at (800) USC-CARE (800-872-2273).

Studies currently open for enrollment:

  • Study of Tysabri in Early Relapsing Remitting Multiple Sclerosis in Anti-JCV Antibody Negative Patients
  • MS Study Evaluating Safety and Efficacy of Two Doses of Fingolimod Versus Copaxone
  • Exploratory Study to Assess Clinical Response to Gilenya® (Fingolimod) in Relapsing Remitting Hispanic Multiple Sclerosis Forms
  • Assessing Induction of Type II (M2) Monocytes/Macrophages in Patients Receiving Gilenya
  • Ampyra in Female Sexual Function
  • Hispanic Ancestry Multiple Sclerosis Registry at USC

Ongoing studies:

  • An Extension Protocol for Multiple Sclerosis Patients Who Participated in Genzyme-Sponsored Studies of Alemtuzumab
  • John Cunningham Virus (JCV) Antibody Study of Multiple Sclerosis (MS) Patients With Relapsing Forms of MS Receiving Treatment With Tysabri

 

[php] function trunc($phrase, $max_words) {
$phrase_array = explode(‘ ‘,$phrase);
if(count($phrase_array) > $max_words && $max_words > 0)
$phrase = implode(‘ ‘,array_slice($phrase_array, 0, $max_words)).’…’;
return $phrase;
}

$NctIdArray = array(“NCT03111394”, “NCT01706107”, “NCT01633112”, “NCT01592097”, “NCT02225977”, “NCT00930553”, “NCT01070836”);

// loop through the items in the rss feed, individually
foreach($NctIdArray as $trialID) {

// define the directory and the name of the xml file
$xml_file2 = ‘http://clinicaltrials.gov/show/NCT01307332?displayxml=true’;

// replace the xml_file2 with the new Trial ID of next item in rss feed
$xml_file3 = substr_replace($xml_file2,$trialID,31,11);

// load the content of the XML file and create a new XML object
$xmlobj2 = simplexml_load_file($xml_file3);

// load the clinical trial variables (title, summary, link, status) from the xml files
$ct_title = “<h2><span style="color: #990000;">” . $xmlobj2->brief_title . “</span></h2>”;
$ct_summary = “<p>” . $xmlobj2->brief_summary->textblock . “</p>”;
$ct_summary_repl = str_replace(“
“,””, $ct_summary);
$ct_link = “Click <a href="”. $xmlobj2->required_header->url . “" target="_blank">here</a> to be directed to the clinicaltrials.gov website for complete and detailed information about this trial.<br /><br />”;
$ct_usc_contact = “<div style="font-size: 11px; font-weight: bold; line-height: 15px !important; ">For information about this clinical trial here at USC or to see if you qualify, contact Jose Aparicio by phone at (323) 442-6833 for more information.</div><div class="clear"></div>”;
$ct_status = $xmlobj2->overall_status;
$ct_eligibility = $xmlobj2->eligibility->criteria->textblock;
$spacer = “<div style="margin-bottom: 60px; "></div>”;

// set the clinical trial status variables (active, active not recruiting, completed, recruiting)
$ct_status_active = “<span style="color: #FFF; background-color: #009884; padding: 10px; ">” . $xmlobj2->overall_status . “</span><br /><br />”;
$ct_status_activeNR = “<span style="color: #FFF; background-color: #ec950f; padding: 10px; ">” . $xmlobj2->overall_status . “</span><br /><br />”;
$ct_status_completed = “<span style="color: #FFF; background-color: #db2f0b; padding: 10px; ">” . $xmlobj2->overall_status . “</span><br /><br />”;
$ct_status_recruiting = “<span style="color: #FFF; background-color: #009884; padding: 10px; ">” . $xmlobj2->overall_status . “</span><br /><br />”;

echo htmlspecialchars_decode($ct_title);
echo htmlspecialchars_decode($ct_summary_repl);
echo htmlspecialchars_decode($ct_usc_contact);[/php]

[php] echo htmlspecialchars_decode($ct_eligibility); [/php]
[php] echo htmlspecialchars_decode($ct_link);

// determine the status of the clinical trial and display the correct variable
if ($ct_status == “Recruiting”):
echo htmlspecialchars_decode($ct_status_recruiting);
elseif ($ct_status == “Active, not recruiting”):
echo htmlspecialchars_decode($ct_status_activeNR);
elseif ($ct_status == “Active”):
echo htmlspecialchars_decode($ct_status_active);
elseif ($ct_status == “Completed”):
echo htmlspecialchars_decode($ct_status_completed);
endif;

echo htmlspecialchars_decode($spacer);
}

[/php]
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Keck Medicine of USC is the University of Southern California’s medical enterprise, one of only two university-owned academic medical centers in the Los Angeles area.